TEC

Across TCGA pan-cancer cohorts, TEC RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TEC data layer compared with 5 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TEC RNA is associated with better overall survival. In most high-consensus cancer types, elevated TEC expression acts as an unfavorable survival marker, although some lineages such as SKCM and OV show a favorable association.

SKCM, OV, and KIRC are the cancer types where TEC RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	III,IV	0.564	0.291	.001	55	view →
OV	OS	Tertile	II,III,IV	0.726	0.618	.014	52	view →
KIRC	DFS	Quartile	All	0.831	0.525	.001	49	view →
UCEC	OS	Quartile	III,IV	0.763	0.480	.009	30	view →
KICH	DFS	Quartile	III,IV	0.178	1.000	.003	30	view →
PAAD	OS	Quartile	All	0.247	0.660	.005	21	view →
ACC	DFS	Median	II,III,IV	0.499	0.741	.008	21	view →
STAD	DFS	Quartile	III,IV	0.605	0.340	.022	16	view →
LUSC	DFS	Median	All	0.732	0.837	.015	10	view →
LIHC	DFS	Median	All	0.491	0.590	.012	10	view →
MESO	DFS	Tertile	IV	0.134	0.473	.019	10	view →
READ	DFS	Quartile	All	0.803	0.359	.027	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TEC–SKCM (OS)

Open the SKCM breakdown →