TEC

Across TCGA cell cohorts, TEC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,903 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TEC-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Mitochondrial calcium ion transmembrane transport, and Phosphatidylinositol biosynthetic process. Each is linked with TEC in more than 8 cancer types. Because this analysis shows association rather than direction, both TEC-to-partner and partner-to-TEC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by TEC-low versus TEC-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEC→partner) and Y-score (partner→TEC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cytoplasmic pattern recognition receptor signaling pathway →	+0.064	+0.878	<.001	<.001	3	9
URINARY_TRACT	Mitochondrial calcium ion transmembrane transport →	+0.082	+0.624	<.001	.002	3	8
STOMACH	Phosphatidylinositol biosynthetic process →	+0.059	+1.019	.001	.005	3	8
OVARY	Regulation of stress-activated protein kinase signaling cascade →	+0.117	+0.752	<.001	<.001	3	8
LUNG_SCLC	Xenophagy →	+0.156	+1.063	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Forebrain ventricular zone progenitor cell division →	-1.076	-0.970	.003	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,903 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by TEC expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →