TDP2

Across TCGA patient cohorts, TDP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,798 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TDP2-associated proteins across cancer lineages are NELFB, PAIP2B, and PGD. Each is linked with TDP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TDP2-to-partner and partner-to-TDP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TDP2 versus NELFB in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TDP2→partner) and Y-score (partner→TDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NELFB →	+0.193	+0.435	<.001	<.001	3	3
HNSC	PAIP2B →	-0.495	-0.588	<.001	.009	3	3
LSCC	PGD →	+0.587	+0.680	<.001	<.001	3	3
LSCC	AKR1B10 →	+2.193	+0.725	<.001	<.001	3	3
HNSC	RANBP9 →	+0.224	+0.441	<.001	.001	3	3
OV	CMTR1 →	+0.349	+0.542	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,798 associations by consensus.

TDP2 vs NELFB — LSCC

Explore this scatter interactively →