Across TCGA patient cohorts, TCP10L3 mutation is significantly associated with the RNA expression of many other genes, with 1,699 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCP10L3-associated genes across cancer lineages are KYNUP1, LINC02559, and NOX3. Each is linked with TCP10L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCP10L3-to-partner and partner-to-TCP10L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP10L3→partner) and Y-score (partner→TCP10L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	KYNUP1 →	+0.039	+6.618	<.001	.001	3	2
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
CESC	NOX3 →	+1.363	+4.874	<.001	.002	3	2
UCEC	CCDC51 →	+0.504	+2.716	.004	.003	3	2
UCEC	PPP1R36 →	-0.547	-2.415	.006	.003	3	2
UCEC	COG1 →	+0.367	+2.880	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,699 associations by consensus.

Exploration

TCP10L3 survival (RNA) · tumor vs normal (RNA) · all TCP10L3 data types