Across TCGA pan-cancer cohorts, TCP10L3 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated TCP10L3 data layer compared with 2 for mutation status.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TCP10L3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TCP10L3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and COAD show a favorable association.
BLCA, SKCM, and COAD are the cancer types where TCP10L3 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.