KYNUP1

Q-omics provides the consensus-scored KYNUP1 profile across patient tissues and cancer cell-line models. KYNUP1 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, KYNUP1 RNA expression shows 3,905 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ESCA, and STAD as cancer lineages where KYNUP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes KYNUP1 survival associations across molecular data types. KYNUP1 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

KYNUP1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	LIHC (54)	view →

This table ranks reproducible KYNUP1 RNA expression–survival associations across cancer types. High KYNUP1 expression shows unfavorable associations in LIHC, MESO, COAD and LUAD, but favorable associations in ESCA and GBM. The ESCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify ESCA as the clearest survival context for KYNUP1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	II,III,IV	0.689	0.426	.002	54	view →
LIHC	OS	Tertile	II,III,IV	0.118	0.716	.003	54	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	45	view →
COAD	DFS	Tertile	All	0.175	0.699	.004	39	view →
LUAD	OS	Tertile	III,IV	0.083	0.680	<.001	36	view →
GBM	OS	Tertile	All	0.512	0.244	.006	30	view →

Pink = unfavorable, green = favorable. all 11 lineages →

KYNUP1-ESCA (DFS)

Explore this curve interactively →