TCP10L

Across TCGA cell cohorts, TCP10L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,039 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TCP10L-associated GO terms across cancer lineages are COPII vesicle coating, Geranyl diphosphate metabolic process, and Regulation of actin filament depolymerization. Each is linked with TCP10L in more than 6 cancer types. Because this analysis shows association rather than direction, both TCP10L-to-partner and partner-to-TCP10L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII vesicle coating grouped by TCP10L-low versus TCP10L-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP10L→partner) and Y-score (partner→TCP10L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	COPII vesicle coating →	+0.081	+0.540	<.001	<.001	3	7
BONE	Geranyl diphosphate metabolic process →	+0.115	+0.697	.001	.001	3	7
BREAST	Regulation of actin filament depolymerization →	-0.101	-0.414	<.001	<.001	3	7
BONE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.052	+0.587	.002	.009	3	7
BONE	mRNA splicing, via spliceosome →	+0.052	+0.587	.002	.009	3	7
UPPER_AERODIGESTIVE_TRACT	Vesicle targeting, rough ER to cis-Golgi →	+0.094	+0.275	.005	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,039 associations by consensus.

COPII vesicle coating by TCP10L expression — BREAST

Explore this box plot interactively →