TCP1

Across TCGA patient cohorts, TCP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,459 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TCP1-associated genes across cancer lineages are MRPL18, RPF2, and ACAT2. Each is linked with TCP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TCP1-to-partner and partner-to-TCP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCP1 versus MRPL18 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP1→partner) and Y-score (partner→TCP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL18 →	+0.717	+0.197	<.001	<.001	3	7
LSCC	RPF2 →	+0.508	+0.176	<.001	<.001	3	6
LSCC	ACAT2 →	+0.661	+0.143	<.001	<.001	3	6
UCEC	GTF3C6 →	+0.592	+0.250	<.001	<.001	3	5
GBM	LTV1 →	+0.472	+0.168	<.001	<.001	3	5
LUAD	MTFR2 →	+0.862	+0.261	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,459 associations by consensus.

TCP1 vs MRPL18 — UCEC

Explore this scatter interactively →