TCF7L1-IT1

Across TCGA patient cohorts, TCF7L1-IT1 RNA expression is significantly associated with the RNA expression of many other genes, with 12,004 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TCF7L1-IT1-associated genes across cancer lineages are TCF7L1, ZNF70, and TAS2R31. Each is linked with TCF7L1-IT1 in more than 21 cancer types. Because this analysis shows association rather than direction, both TCF7L1-IT1-to-partner and partner-to-TCF7L1-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCF7L1-IT1 versus TCF7L1 in TGCT, with a Pearson correlation of 0.62.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF7L1-IT1→partner) and Y-score (partner→TCF7L1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	TCF7L1 →	+1.700	+0.312	<.001	<.001	3	22
THYM	ZNF70 →	+0.633	+0.222	<.001	<.001	3	17
THYM	TAS2R31 →	+0.909	+0.236	<.001	<.001	2	17
TGCT	ZNF850 →	+0.801	+0.207	<.001	<.001	3	16
TGCT	TUT4 →	+0.649	+0.363	<.001	<.001	3	16
TGCT	AGO4 →	+0.699	+0.276	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,004 associations by consensus.

TCF7L1-IT1 vs TCF7L1 — TGCT

Explore this scatter interactively →