TCF15

Across TCGA patient cohorts, TCF15 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCF15-associated genes across cancer lineages are RNA5SP205, IGHD1-26, and IGHD6-6. Each is linked with TCF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCF15-to-partner and partner-to-TCF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP205 grouped by TCF15-low versus TCF15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF15→partner) and Y-score (partner→TCF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP205 →	+0.607	+5.852	<.001	.003	3	1
UCEC	IGHD1-26 →	+1.890	+5.484	<.001	.005	3	1
UCEC	IGHD6-6 →	+1.667	+5.420	<.001	.005	3	1
UCEC	LINC02353 →	+0.361	+5.484	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RNA5SP205 by TCF15 expression — UCEC

Explore this box plot interactively →