TBL1X

Across TCGA cell cohorts, TBL1X mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBL1X-associated genes across cancer lineages are ASZ1, FAM47C, and HRG. Each is linked with TBL1X in more than 1 cancer types. Because this analysis shows association rather than direction, both TBL1X-to-partner and partner-to-TBL1X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASZ1 grouped by TBL1X-low versus TBL1X-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBL1X→partner) and Y-score (partner→TBL1X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ASZ1 →	+0.083	+2.982	.004	.007	3	2
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Leukemia	HRG →	+0.321	+3.177	<.001	.004	3	1
BLOOD_Leukemia	ATP1A4 →	+0.442	+3.594	<.001	.007	3	1
BLOOD_Leukemia	KAAG1 →	+0.065	+3.177	<.001	.004	3	1
BLOOD_Leukemia	MAGEE2 →	+0.191	+3.177	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

ASZ1 by TBL1X expression — BLOOD_Leukemia

Explore this box plot interactively →