TBCCD1

Across TCGA cell cohorts, TBCCD1 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBCCD1-associated genes across cancer lineages are KCNG4, TEX43, and PLA2G3. Each is linked with TBCCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBCCD1-to-partner and partner-to-TBCCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNG4 grouped by TBCCD1-low versus TBCCD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCCD1→partner) and Y-score (partner→TBCCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KCNG4 →	+0.004	+4.539	.009	.007	3	1
BLOOD_Leukemia	TEX43 →	+0.105	+4.969	<.001	.003	3	1
LARGE_INTESTINE	PLA2G3 →	+0.915	+3.215	.007	.009	3	1
LARGE_INTESTINE	ZNF330 →	+0.530	+3.067	.005	.009	3	1
LARGE_INTESTINE	GALR3 →	+0.104	+3.602	<.001	.005	3	1
LARGE_INTESTINE	UBE2Q2 →	+0.893	+3.215	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

KCNG4 by TBCCD1 expression — BLOOD_Leukemia

Explore this box plot interactively →