TBCB

Across TCGA cell cohorts, TBCB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,793 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBCB-associated GO terms across cancer lineages are Cell division, Anatomical structure homeostasis, and Cytoskeleton-dependent cytokinesis. Each is linked with TBCB in more than 13 cancer types. Because this analysis shows association rather than direction, both TBCB-to-partner and partner-to-TBCB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by TBCB-low versus TBCB-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCB→partner) and Y-score (partner→TBCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cell division →	+0.078	+0.978	.002	.002	3	14
LUNG_NSCLC_LUSC	Anatomical structure homeostasis →	-0.082	-1.311	<.001	<.001	3	12
LIVER	Cytoskeleton-dependent cytokinesis →	+0.079	+0.778	.001	<.001	3	12
BONE	Cytokinesis →	+0.067	+0.881	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Tissue homeostasis →	-0.082	-1.311	<.001	<.001	3	12
URINARY_TRACT	Regulation of sister chromatid segregation →	+0.115	+1.312	.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,793 associations by consensus.

Cell division by TBCB expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →