Across TCGA patient cohorts, TBC1D8 mutation is significantly associated with the RNA expression of many other genes, with 3,379 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D8-associated genes across cancer lineages are CDCA2, PINK1-AS, and SLC25A37. Each is linked with TBC1D8 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D8-to-partner and partner-to-TBC1D8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D8→partner) and Y-score (partner→TBC1D8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CDCA2 →	+0.750	+2.598	.001	.006	3	4
COAD	PINK1-AS →	+0.554	+3.375	<.001	.004	3	3
COAD	SLC25A37 →	+0.518	+2.645	.003	.005	3	3
BRCA	RNU6-855P →	+0.127	+4.201	<.001	.007	3	3
UCEC	RNY3P8 →	-0.558	-1.390	.008	.009	3	3
UCEC	TSPY26P →	-0.456	-1.847	.009	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,379 associations by consensus.

Exploration

TBC1D8 survival (RNA) · tumor vs normal (RNA) · all TBC1D8 data types