TBC1D3F

Across TCGA patient cohorts, TBC1D3F mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. SARC shows the largest number of these associations.

The most reproducible TBC1D3F-associated genes across cancer lineages are SNORD114-31, RNA5SP263, and SNORD114-11. Each is linked with TBC1D3F in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D3F-to-partner and partner-to-TBC1D3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-31 grouped by TBC1D3F-low versus TBC1D3F-high in THYM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3F→partner) and Y-score (partner→TBC1D3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	SNORD114-31 →	+0.573	+5.820	<.001	.002	3	1
THYM	RNA5SP263 →	+1.096	+5.209	<.001	.006	3	1
THYM	SNORD114-11 →	+0.572	+5.820	<.001	.002	3	1
THYM	RNU6-1327P →	+0.560	+4.974	<.001	.009	3	1
THYM	RNU6-1316P →	+0.387	+4.974	<.001	.009	3	1
THYM	MIR585 →	+0.471	+5.209	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

SNORD114-31 by TBC1D3F expression — THYM

Explore this box plot interactively →