TBC1D3F

Across TCGA pan-cancer cohorts, TBC1D3F RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TBC1D3F data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TBC1D3F RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D3F expression acts as an unfavorable survival marker, although some lineages such as ESCA and CHOL show a favorable association.

KIRC, LIHC, and ACC are the cancer types where TBC1D3F RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.222	0.547	<.001	102	view →
LIHC	OS	Tertile	III,IV	0.103	0.685	<.001	63	view →
ACC	OS	Tertile	IV	0.373	0.788	.004	60	view →
HNSC	DFS	Tertile	III,IV	0.224	0.631	.001	54	view →
ESCA	OS	Tertile	II,III,IV	0.825	0.616	.009	44	view →
PAAD	OS	Tertile	II,III,IV	0.186	0.529	.006	36	view →
LAML	DFS	Tertile	All	0.400	0.608	.015	36	view →
CHOL	OS	Tertile	All	0.898	0.493	.020	30	view →
CESC	OS	Tertile	III,IV	0.561	0.779	.018	24	view →
BLCA	DFS	Tertile	All	0.458	0.297	.018	22	view →
STAD	DFS	Tertile	All	0.311	0.521	.024	21	view →
SKCM	OS	Tertile	II,III,IV	0.974	0.822	.018	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TBC1D3F–KIRC (DFS)

Open the KIRC breakdown →