TBC1D3F

Across TCGA cell cohorts, TBC1D3F mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TBC1D3F-associated genes across cancer lineages are RETN, GALNTL5, and GABRA4. Each is linked with TBC1D3F in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D3F-to-partner and partner-to-TBC1D3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RETN grouped by TBC1D3F-low versus TBC1D3F-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3F→partner) and Y-score (partner→TBC1D3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RETN →	+0.124	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	GALNTL5 →	+0.071	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	GABRA4 →	+0.093	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR2L8 →	+0.015	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	FGF4 →	+0.030	+4.169	.004	.007	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

RETN by TBC1D3F expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →