TBC1D3D

Across TCGA patient cohorts, TBC1D3D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,203 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D3D-associated GO terms across cancer lineages are Peptidyl-arginine modification, Multi-pass transmembrane protein insertion into ER membrane, and Nucleoside triphosphate biosynthetic process. Each is linked with TBC1D3D in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D3D-to-partner and partner-to-TBC1D3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-arginine modification grouped by TBC1D3D-low versus TBC1D3D-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3D→partner) and Y-score (partner→TBC1D3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Peptidyl-arginine modification →	+0.014	+0.078	.001	<.001	3	4
UCEC	Multi-pass transmembrane protein insertion into ER membrane →	+0.044	+0.093	<.001	<.001	3	4
HNSC	Nucleoside triphosphate biosynthetic process →	+0.012	+0.098	.001	<.001	3	4
COAD	Mitotic intra-S DNA damage checkpoint signaling →	+0.023	+0.055	<.001	<.001	3	3
UCEC	miRNA-mediated gene silencing by mRNA destabilization →	-0.047	-0.156	<.001	<.001	3	3
THYM	mRNA 3'-splice site recognition →	+0.027	+0.171	<.001	.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,203 associations by consensus.

Peptidyl-arginine modification by TBC1D3D expression — HNSC

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