TBC1D3D

Across TCGA pan-cancer cohorts, TBC1D3D RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated TBC1D3D data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher TBC1D3D RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D3D expression acts as an unfavorable survival marker, although some lineages such as STAD and BLCA show a favorable association.

KIRP, STAD, and BRCA are the cancer types where TBC1D3D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	IV	0.166	0.523	.004	41	view →
STAD	DFS	Tertile	III,IV	0.709	0.271	.005	36	view →
BRCA	OS	Tertile	IV	0.383	0.802	.016	36	view →
BLCA	OS	Tertile	All	0.607	0.364	.002	31	view →
UCEC	DFS	Tertile	All	0.712	0.854	.001	30	view →
KIRC	DFS	Tertile	IV	0.233	0.545	.018	18	view →
UVM	OS	Tertile	All	0.321	0.695	.028	18	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	18	view →
COAD	DFS	Tertile	II,III,IV	0.203	0.498	.002	18	view →
LUSC	DFS	Tertile	III,IV	1.000	0.362	.020	18	view →
UCS	DFS	Tertile	IV	0.981	0.510	.020	18	view →
ESCA	DFS	Tertile	III,IV	0.630	0.358	.012	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

TBC1D3D–KIRP (DFS)

Open the KIRP breakdown →