TBC1D3D

Across TCGA pan-cancer cohorts, TBC1D3D RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TBC1D3D’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TBC1D3D RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TBC1D3D is over-expressed in tumor.

KIRC and BLCA are the cancer types where TBC1D3D tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TBC1D3D RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.036	.014	4	view →
BLCA	Female	III,IV	+0.020	.025	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TBC1D3D–KIRC

Open the KIRC breakdown →