TBC1D3B

Across TCGA patient cohorts, TBC1D3B mutation is significantly associated with the RNA expression of many other genes, with 1,017 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D3B-associated genes across cancer lineages are ZNF736P7Y, CHEK2P5, and CD24P1. Each is linked with TBC1D3B in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D3B-to-partner and partner-to-TBC1D3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF736P7Y grouped by TBC1D3B-low versus TBC1D3B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3B→partner) and Y-score (partner→TBC1D3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF736P7Y →	+0.064	+8.055	<.001	.007	3	2
COAD	CHEK2P5 →	+0.286	+6.003	.003	.002	3	2
COAD	CD24P1 →	+0.302	+5.357	<.001	.006	3	2
LUSC	AQP7P4 →	+0.057	+5.081	<.001	.004	3	2
SKCM	LINC01861 →	+0.240	+5.771	<.001	.003	3	2
BRCA	MIR8052 →	+0.541	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,017 associations by consensus.

ZNF736P7Y by TBC1D3B expression — BRCA

Explore this box plot interactively →