TBC1D2B

Across TCGA patient cohorts, TBC1D2B protein abundance is significantly associated with the RNA expression of many other genes, with 20,448 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBC1D2B-associated genes across cancer lineages are CYTH4, RASAL3, and PIK3CG. Each is linked with TBC1D2B in more than 9 cancer types. Because this analysis shows association rather than direction, both TBC1D2B-to-partner and partner-to-TBC1D2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D2B versus CYTH4 in GBM, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D2B→partner) and Y-score (partner→TBC1D2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.106	+0.451	<.001	<.001	3	10
GBM	RASAL3 →	+0.879	+0.442	<.001	<.001	3	10
GBM	PIK3CG →	+0.929	+0.427	<.001	<.001	3	10
GBM	CD4 →	+1.163	+0.435	<.001	<.001	3	10
GBM	MS4A6A →	+1.536	+0.459	<.001	<.001	3	10
GBM	MS4A4A →	+1.543	+0.432	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,448 associations by consensus.

TBC1D2B vs CYTH4 — GBM

Explore this scatter interactively →