TBC1D24

Across TCGA patient cohorts, TBC1D24 mutation is significantly associated with the RNA expression of many other genes, with 2,894 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D24-associated genes across cancer lineages are COX15, EI24, and SAR1B. Each is linked with TBC1D24 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D24-to-partner and partner-to-TBC1D24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX15 grouped by TBC1D24-low versus TBC1D24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D24→partner) and Y-score (partner→TBC1D24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COX15 →	+0.442	+3.753	<.001	<.001	3	3
UCEC	EI24 →	+0.377	+2.000	.005	.001	3	3
UCEC	SAR1B →	+0.455	+2.321	<.001	<.001	3	3
UCEC	MPPE1 →	+0.429	+2.212	<.001	.001	3	3
UCEC	BROX →	+0.436	+2.526	.005	.001	3	3
UCEC	HSPA4L →	+0.605	+2.431	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,894 associations by consensus.

COX15 by TBC1D24 expression — UCEC

Explore this box plot interactively →