TBC1D24

Across TCGA cell cohorts, TBC1D24 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,794 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TBC1D24-associated GO terms across cancer lineages are Regulation of chromatin organization, Pre-mRNA catabolic process, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with TBC1D24 in more than 15 cancer types. Because this analysis shows association rather than direction, both TBC1D24-to-partner and partner-to-TBC1D24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by TBC1D24-low versus TBC1D24-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D24→partner) and Y-score (partner→TBC1D24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of chromatin organization →	+0.117	+0.928	<.001	<.001	3	16
BONE	Pre-mRNA catabolic process →	+0.226	+0.921	<.001	<.001	3	16
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.154	+0.789	<.001	<.001	3	15
BREAST	Positive regulation of neuron migration →	+0.101	+1.018	<.001	<.001	3	15
URINARY_TRACT	Positive regulation of telomere maintenance →	+0.058	+0.804	.009	<.001	3	15
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.175	+0.870	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,794 associations by consensus.

Regulation of chromatin organization by TBC1D24 expression — LIVER

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