TBC1D16

Across TCGA patient cohorts, TBC1D16 mutation is significantly associated with the RNA expression of many other genes, with 2,767 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D16-associated genes across cancer lineages are RN7SL326P, IGHVIV-44-1, and EXOSC8. Each is linked with TBC1D16 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D16-to-partner and partner-to-TBC1D16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL326P grouped by TBC1D16-low versus TBC1D16-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D16→partner) and Y-score (partner→TBC1D16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL326P →	+0.321	+2.781	<.001	.007	3	3
LIHC	IGHVIV-44-1 →	+0.184	+5.108	<.001	.008	3	3
UCEC	EXOSC8 →	+0.451	+2.158	<.001	<.001	3	3
COAD	IREB2 →	+0.637	+3.237	.003	.009	3	3
UCEC	GTF2B →	+0.394	+2.191	.001	<.001	3	3
UCEC	GTF2A2 →	+0.383	+3.960	.006	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,767 associations by consensus.

RN7SL326P by TBC1D16 expression — COAD

Explore this box plot interactively →