Across TCGA patient cohorts, TAS2R40 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,222 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TAS2R40-associated GO terms across cancer lineages are Regulation of small GTPase mediated signal transduction, Phosphatidylinositol biosynthetic process, and Regulation of protein serine/threonine kinase activity. Each is linked with TAS2R40 in more than 15 cancer types. Because this analysis shows association rather than direction, both TAS2R40-to-partner and partner-to-TAS2R40 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R40→partner) and Y-score (partner→TAS2R40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of small GTPase mediated signal transduction →	+0.046	+0.098	<.001	.005	2	16
STAD	Phosphatidylinositol biosynthetic process →	+0.044	+0.048	<.001	<.001	3	15
ESCA	Regulation of protein serine/threonine kinase activity →	+0.042	+0.093	<.001	<.001	3	15
STAD	Establishment of cell polarity →	+0.042	+0.039	<.001	<.001	3	14
STAD	Vacuolar transport →	+0.065	+0.071	<.001	<.001	3	14
ESCA	Protein localization to vacuole →	+0.049	+0.062	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,222 associations by consensus.

Exploration

TAS2R40 survival (RNA) · tumor vs normal (RNA) · all TAS2R40 data types