TAS1R3

Across TCGA patient cohorts, TAS1R3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,130 significant associations in total. LGG shows the largest number of these associations.

The most reproducible TAS1R3-associated GO terms across cancer lineages are T cell receptor signaling pathway, B cell mediated immunity, and Immunoglobulin production. Each is linked with TAS1R3 in more than 22 cancer types. Because this analysis shows association rather than direction, both TAS1R3-to-partner and partner-to-TAS1R3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell receptor signaling pathway grouped by TAS1R3-low versus TAS1R3-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS1R3→partner) and Y-score (partner→TAS1R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	T cell receptor signaling pathway →	+0.093	+1.214	<.001	<.001	3	23
SCLC	B cell mediated immunity →	+0.082	+1.025	<.001	.001	3	23
LAML	Immunoglobulin production →	+0.071	+0.630	<.001	<.001	3	21
SCLC	Negative regulation of leukocyte apoptotic process →	+0.115	+1.094	<.001	<.001	3	21
SCLC	B cell activation →	+0.073	+1.086	<.001	<.001	3	21
SCLC	Regulation of CD4-positive, alpha-beta T cell differentiation →	+0.085	+1.255	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,130 associations by consensus.

T cell receptor signaling pathway by TAS1R3 expression — SCLC

Explore this box plot interactively →