TAOK2

Across TCGA cell cohorts, TAOK2 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAOK2-associated genes across cancer lineages are MAP1LC3C, SSTR4, and CLDN8. Each is linked with TAOK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAOK2-to-partner and partner-to-TAOK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAP1LC3C grouped by TAOK2-low versus TAOK2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAOK2→partner) and Y-score (partner→TAOK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MAP1LC3C →	+0.033	+2.948	.001	.008	3	2
SKIN	SSTR4 →	+0.048	+3.347	<.001	.005	3	1
BLOOD_Leukemia	CLDN8 →	+0.011	+4.819	<.001	<.001	3	1
BLOOD_Leukemia	TBPL2 →	+0.087	+4.366	<.001	<.001	3	1
BLOOD_Leukemia	MORN5 →	+0.151	+3.177	<.001	.004	3	1
BLOOD_Leukemia	KHDC3L →	+0.153	+3.607	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

MAP1LC3C by TAOK2 expression — BLOOD_Leukemia

Explore this box plot interactively →