TAOK2

Across TCGA pan-cancer cohorts, TAOK2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TAOK2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TAOK2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAOK2 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, HNSC, and LIHC are the cancer types where TAOK2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAOK2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.719	<.001	11	view →
HNSC	All	III,IV	+0.674	<.001	11	view →
LIHC	Female	II,III,IV	+1.525	<.001	9	view →
STAD	Male	II,III,IV	+1.018	<.001	8	view →
KIRP	All	IV	+0.879	<.001	8	view →
LUSC	Female	All	−0.827	<.001	6	view →
LUAD	Male	All	−0.561	<.001	5	view →
BLCA	All	All	+0.379	.010	5	view →
BRCA	All	All	+0.217	.004	4	view →
CHOL	All	All	+2.202	<.001	3	view →
ESCA	Female	All	+0.963	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TAOK2–KIRC

Open the KIRC breakdown →