Across TCGA patient cohorts, TANGO2 RNA expression is significantly associated with the mutation status of many other genes, with 11,036 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TANGO2-associated genes across cancer lineages are TP53, LTBP2, and RASGRF2. Each is linked with TANGO2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TANGO2-to-partner and partner-to-TANGO2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TANGO2→partner) and Y-score (partner→TANGO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+1.055	+0.331	<.001	<.001	3	6
LUSC	LTBP2 →	+3.193	+0.443	.009	.002	3	4
UCEC	RASGRF2 →	+1.898	+0.411	<.001	<.001	3	4
UCEC	TPO →	+1.981	+0.266	<.001	.002	3	4
UCEC	ARHGEF6 →	+1.439	+0.269	<.001	.002	3	4
UCEC	FAM135B →	+1.038	+0.311	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,036 associations by consensus.

Exploration

TANGO2 survival (RNA) · tumor vs normal (RNA) · all TANGO2 data types