TAMM41

Across TCGA pan-cancer cohorts, TAMM41 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated TAMM41 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TAMM41 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAMM41 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where TAMM41 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
CCRCC	OS	Median	All	0.911	0.756	.032	6	view →
PDAC	DFS	Median	III,IV	0.883	0.480	.010	6	view →
LSCC	OS	Quartile	All	1.000	0.915	.036	5	view →
LUAD	OS	Quartile	All	0.325	0.739	.006	4	view →
HNSC	OS	Quartile	All	0.557	0.768	.010	4	view →
UCEC	DFS	Median	All	0.936	1.000	.022	2	view →
GBM	DFS	Quartile	All	0.292	0.485	.009	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

TAMM41–COAD (DFS)

Open the COAD breakdown →