TAMM41

Across TCGA pan-cancer cohorts, TAMM41 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of TAMM41’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TAMM41 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAMM41 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

COAD, LIHC, and STAD are the cancer types where TAMM41 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAMM41 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.964	<.001	11	view →
LIHC	Female	II,III,IV	+0.661	<.001	8	view →
STAD	All	II,III,IV	+0.465	<.001	7	view →
THCA	All	All	−0.222	<.001	6	view →
KIRC	All	II,III,IV	−0.190	.001	6	view →
CHOL	Male	All	+1.140	<.001	5	view →
READ	Female	All	+0.882	<.001	5	view →
BLCA	All	All	+0.519	.005	5	view →
LUSC	Male	II,III,IV	+0.238	.017	3	view →
HNSC	Female	All	−0.326	.016	2	view →
BRCA	All	IV	−0.125	.043	2	view →
KIRP	All	II,III,IV	+0.263	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

TAMM41–COAD

Open the COAD breakdown →