TAMM41

Across TCGA patient cohorts, TAMM41 mutation is significantly associated with the RNA expression of many other genes, with 1,671 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAMM41-associated genes across cancer lineages are ATP6V1E1P2, RN7SKP125, and PPP1R2P2. Each is linked with TAMM41 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAMM41-to-partner and partner-to-TAMM41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V1E1P2 grouped by TAMM41-low versus TAMM41-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAMM41→partner) and Y-score (partner→TAMM41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ATP6V1E1P2 →	+0.165	+5.034	<.001	.002	3	2
SKCM	RN7SKP125 →	+0.160	+6.219	<.001	<.001	3	2
CESC	PPP1R2P2 →	+0.096	+4.934	<.001	.002	3	1
CESC	LINC01519 →	+0.018	+4.669	.004	.007	3	1
CESC	MTND5P5 →	+0.090	+5.144	<.001	.003	3	1
CESC	MIR4507 →	+0.656	+4.705	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,671 associations by consensus.

ATP6V1E1P2 by TAMM41 expression — SKCM

Explore this box plot interactively →