Across TCGA patient cohorts, TAL2 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TAL2-associated genes across cancer lineages are RNU6-91P, RN7SL248P, and MIR6752. Each is linked with TAL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAL2-to-partner and partner-to-TAL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAL2→partner) and Y-score (partner→TAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-91P →	+0.565	+3.302	.001	.009	3	1
UCEC	RN7SL248P →	+0.141	+4.400	<.001	.006	3	1
SKCM	MIR6752 →	+0.498	+5.199	<.001	.003	3	1
SKCM	ELAVL4-AS1 →	+0.244	+4.440	.002	.006	3	1
SKCM	RNU7-80P →	+0.710	+4.680	<.001	.007	3	1
SKCM	RN7SL854P →	+0.233	+4.970	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

TAL2 survival (RNA) · tumor vs normal (RNA) · all TAL2 data types