TAGLN2

Across TCGA patient cohorts, TAGLN2 mutation is significantly associated with the RNA expression of many other genes, with 807 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAGLN2-associated genes across cancer lineages are SLC2A13P1, RNA5SP148, and SPANXN3. Each is linked with TAGLN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAGLN2-to-partner and partner-to-TAGLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC2A13P1 grouped by TAGLN2-low versus TAGLN2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAGLN2→partner) and Y-score (partner→TAGLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SLC2A13P1 →	+0.470	+4.721	<.001	.004	3	3
BRCA	RNA5SP148 →	+0.234	+7.731	.001	.009	3	2
SKCM	SPANXN3 →	+0.818	+4.296	<.001	.008	3	2
SKCM	RNU6-227P →	+0.316	+5.080	<.001	.004	3	2
SKCM	OR13C3 →	+0.035	+5.080	<.001	.004	3	2
SKCM	SEPTIN14P24 →	+0.192	+4.680	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 807 associations by consensus.

SLC2A13P1 by TAGLN2 expression — COAD

Explore this box plot interactively →