TAF8

Across TCGA cell cohorts, TAF8 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAF8-associated genes across cancer lineages are TEX55, PRM3, and RBMY1J. Each is linked with TAF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF8-to-partner and partner-to-TAF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX55 grouped by TAF8-low versus TAF8-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF8→partner) and Y-score (partner→TAF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TEX55 →	+0.037	+4.321	<.001	.009	3	1
CNS	PRM3 →	+0.133	+4.754	<.001	.005	3	1
CNS	RBMY1J →	+0.047	+4.832	<.001	.002	3	1
CNS	USP17L11 →	+0.005	+5.357	<.001	.001	3	1
CNS	USP17L20 →	+0.005	+5.357	<.001	.001	3	1
CNS	USP17L18 →	+0.005	+5.357	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

TEX55 by TAF8 expression — CNS

Explore this box plot interactively →