TAF2

Across TCGA patient cohorts, TAF2 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF2-associated genes across cancer lineages are ACC1, PCNA, and Annexin_VII. Each is linked with TAF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAF2-to-partner and partner-to-TAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by TAF2-low versus TAF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF2→partner) and Y-score (partner→TAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.264	+1.247	.033	.045	3	3
UCEC	PCNA →	+0.216	+2.906	.003	.001	3	3
UCEC	Annexin_VII →	-0.121	-1.807	.010	.004	3	2
UCEC	ASNS →	+0.378	+1.678	.002	.021	3	2
UCEC	Bak →	+0.177	+2.000	.038	.029	3	2
UCEC	Bcl-2 →	-0.237	-1.980	.045	.030	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

ACC1 by TAF2 expression — UCEC

Explore this box plot interactively →