TAF2

Across TCGA cell cohorts, TAF2 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TAF2-associated genes across cancer lineages are TPD52L3, SEC14L4, and KRT2. Each is linked with TAF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF2-to-partner and partner-to-TAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPD52L3 grouped by TAF2-low versus TAF2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF2→partner) and Y-score (partner→TAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TPD52L3 →	+0.225	+3.944	<.001	.006	3	2
SOFT_TISSUE	SEC14L4 →	+0.510	+3.999	<.001	.004	3	1
SOFT_TISSUE	KRT2 →	+0.839	+4.295	<.001	.002	3	1
SOFT_TISSUE	DEFB103A →	+0.207	+3.635	<.001	.007	3	1
SOFT_TISSUE	CCDC185 →	+0.038	+3.635	<.001	.007	3	1
SOFT_TISSUE	OR52N4 →	+0.068	+5.297	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

TPD52L3 by TAF2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →