TAF1A

Across TCGA patient cohorts, TAF1A mutation is significantly associated with the RNA expression of many other genes, with 902 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF1A-associated genes across cancer lineages are MIR8075, DNM1P28, and MIR5681A. Each is linked with TAF1A in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF1A-to-partner and partner-to-TAF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8075 grouped by TAF1A-low versus TAF1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF1A→partner) and Y-score (partner→TAF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8075 →	+0.598	+2.011	.008	.003	3	2
COAD	DNM1P28 →	+0.068	+4.537	<.001	.006	3	2
BLCA	MIR5681A →	+0.483	+7.640	<.001	.009	3	2
SKCM	MIR4769 →	+0.585	+4.614	<.001	.006	3	2
SKCM	USH2A-AS2 →	+0.115	+4.302	<.001	.002	3	2
UCEC	OR10G7 →	+0.031	+2.901	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 902 associations by consensus.

MIR8075 by TAF1A expression — UCEC

Explore this box plot interactively →