TAF1A

Across TCGA pan-cancer cohorts, TAF1A RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated TAF1A data layer compared with 8 for mutation status.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher TAF1A RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAF1A expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

CESC, KIRP, and ACC are the cancer types where TAF1A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.421	0.671	<.001	104	view →
KIRP	OS	Tertile	All	0.631	0.826	<.001	92	view →
ACC	DFS	Tertile	All	0.170	0.783	<.001	59	view →
THCA	OS	Tertile	II,III,IV	0.308	1.000	.003	35	view →
SARC	OS	Median	All	0.426	0.597	<.001	33	view →
KIRC	DFS	Tertile	All	0.890	0.700	<.001	32	view →
UCS	OS	Median	III,IV	0.760	0.392	.002	32	view →
STAD	DFS	Median	II,III,IV	0.359	0.653	.001	28	view →
PAAD	OS	Tertile	All	0.362	0.642	.007	25	view →
LUAD	OS	Quartile	All	0.724	0.845	.004	24	view →
KICH	OS	Median	II,III,IV	0.811	0.966	.014	23	view →
READ	DFS	Median	All	0.681	0.354	.011	23	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

TAF1A–CESC (DFS)

Open the CESC breakdown →