TACC3

Across TCGA patient cohorts, TACC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,771 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TACC3-associated proteins across cancer lineages are RRM2, PTPN2_S304, and SMC2. Each is linked with TACC3 in more than 9 cancer types. Because this analysis shows association rather than direction, both TACC3-to-partner and partner-to-TACC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TACC3 versus RRM2 in LUAD, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TACC3→partner) and Y-score (partner→TACC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+0.897	+0.788	<.001	<.001	3	10
GBM	PTPN2_S304 →	+0.646	+0.984	<.001	<.001	3	9
GBM	SMC2 →	+0.719	+0.603	<.001	<.001	3	9
GBM	SMC4 →	+1.075	+1.262	<.001	<.001	3	9
LUAD	RFC1_T506 →	+1.164	+0.919	<.001	<.001	3	9
LUAD	RPL12_S38 →	+1.262	+0.758	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,771 associations by consensus.

TACC3 vs RRM2 — LUAD

Explore this scatter interactively →