SYTL4

Across TCGA patient cohorts, SYTL4 mutation is significantly associated with the RNA expression of many other genes, with 5,012 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYTL4-associated genes across cancer lineages are RNA5SP158, MT-RNR2, and KCNK15. Each is linked with SYTL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SYTL4-to-partner and partner-to-SYTL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP158 grouped by SYTL4-low versus SYTL4-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL4→partner) and Y-score (partner→SYTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA5SP158 →	+0.428	+3.691	.002	.008	3	3
UCEC	MT-RNR2 →	-0.442	-1.697	.004	.001	3	3
UCEC	KCNK15 →	-1.064	-2.048	<.001	<.001	3	3
UCEC	ZIC2 →	+1.490	+1.450	<.001	<.001	3	3
OV	SNX3P1Y →	+0.104	+4.922	<.001	.003	3	2
LGG	RPL22P14 →	+0.206	+5.039	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,012 associations by consensus.

RNA5SP158 by SYTL4 expression — STAD

Explore this box plot interactively →