SYT13

Across TCGA cell cohorts, SYT13 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SYT13-associated genes across cancer lineages are OR1L6, OR13C8, and FAM205A. Each is linked with SYT13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT13-to-partner and partner-to-SYT13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by SYT13-low versus SYT13-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT13→partner) and Y-score (partner→SYT13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR1L6 →	+0.011	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.019	+4.078	<.001	.009	3	1
LARGE_INTESTINE	FAM205A →	+0.017	+3.766	.004	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1
SKIN	KCNMB1 →	+0.961	+3.567	<.001	.002	3	1
SKIN	NPAS4 →	+0.121	+2.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR1L6 by SYT13 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →