SYT12

Across TCGA cell cohorts, SYT12 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SYT12-associated genes across cancer lineages are OR9A2, OR6T1, and GHRHR. Each is linked with SYT12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT12-to-partner and partner-to-SYT12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9A2 grouped by SYT12-low versus SYT12-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT12→partner) and Y-score (partner→SYT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR9A2 →	+0.022	+5.209	<.001	.005	3	2
LUNG_NSCLC_LUAD	OR6T1 →	+0.052	+4.887	<.001	.009	3	1
BLOOD_Leukemia	GHRHR →	+0.467	+4.705	<.001	.003	3	1
BLOOD_Leukemia	GIMD1 →	+0.041	+4.152	<.001	.009	3	1
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	VN1R2 →	+0.006	+5.643	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR9A2 by SYT12 expression — BLOOD_Lymphoma

Explore this box plot interactively →