SYS1-DBNDD2

Across TCGA patient cohorts, SYS1-DBNDD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,376 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYS1-DBNDD2-associated proteins across cancer lineages are RALY_S135, SDC1_S287, and EHBP1_S1035. Each is linked with SYS1-DBNDD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SYS1-DBNDD2-to-partner and partner-to-SYS1-DBNDD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYS1-DBNDD2 versus RALY_S135 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYS1-DBNDD2→partner) and Y-score (partner→SYS1-DBNDD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RALY_S135 →	+0.294	+0.166	<.001	.003	3	3
LSCC	SDC1_S287 →	-0.516	-0.163	.007	.005	3	3
GBM	EHBP1_S1035 →	-0.413	-0.248	<.001	.002	3	3
BRCA	FARP1 →	+0.356	+0.302	<.001	<.001	3	3
BRCA	KRT17_S32 →	-1.151	-0.255	.003	.009	3	3
BRCA	MAPK6_S665 →	-0.676	-0.424	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,376 associations by consensus.

SYS1-DBNDD2 vs RALY_S135 — HNSC

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