SYNPO2L

Across TCGA patient cohorts, SYNPO2L protein abundance is significantly associated with the RNA expression of many other genes, with 2,099 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SYNPO2L-associated genes across cancer lineages are MAST1, GRB7, and CD163L1. Each is linked with SYNPO2L in more than 1 cancer types. Because this analysis shows association rather than direction, both SYNPO2L-to-partner and partner-to-SYNPO2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNPO2L versus MAST1 in LSCC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNPO2L→partner) and Y-score (partner→SYNPO2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAST1 →	-0.393	-0.790	.009	.001	3	2
LSCC	GRB7 →	-1.099	-0.665	<.001	.009	3	2
HNSC	CD163L1 →	+0.954	+0.865	.004	<.001	3	2
LUAD	RAB36 →	+1.255	+1.025	.006	.001	3	1
LUAD	RNF40 →	+0.756	+1.025	.005	.001	3	1
LUAD	ABHD17B →	+0.707	+0.933	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,099 associations by consensus.

SYNPO2L vs MAST1 — LSCC

Explore this scatter interactively →