SYNGAP1-AS1

Across TCGA patient cohorts, SYNGAP1-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,118 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SYNGAP1-AS1-associated GO terms across cancer lineages are Regulation of DNA replication, Positive regulation of chromosome organization, and DNA replication. Each is linked with SYNGAP1-AS1 in more than 27 cancer types. Because this analysis shows association rather than direction, both SYNGAP1-AS1-to-partner and partner-to-SYNGAP1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA replication grouped by SYNGAP1-AS1-low versus SYNGAP1-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGAP1-AS1→partner) and Y-score (partner→SYNGAP1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA replication →	+0.054	+0.163	<.001	<.001	3	28
STAD	Positive regulation of chromosome organization →	+0.056	+0.132	<.001	<.001	3	27
STAD	DNA replication →	+0.054	+0.128	<.001	<.001	3	27
STAD	Regulation of double-strand break repair →	+0.045	+0.142	<.001	<.001	3	26
STAD	Positive regulation of DNA repair →	+0.045	+0.141	<.001	<.001	3	26
STAD	Mismatch repair →	+0.046	+0.172	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,118 associations by consensus.

Regulation of DNA replication by SYNGAP1-AS1 expression — ESCA

Explore this box plot interactively →