SYNDIG1L

Across TCGA cell cohorts, SYNDIG1L RNA expression is significantly associated with the go_rna of many other GO terms, with 680 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SYNDIG1L-associated GO terms across cancer lineages are Regulation of autophagosome assembly, Regulation of macroautophagy, and Positive regulation of autophagy. Each is linked with SYNDIG1L in more than 5 cancer types. Because this analysis shows association rather than direction, both SYNDIG1L-to-partner and partner-to-SYNDIG1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of autophagosome assembly grouped by SYNDIG1L-low versus SYNDIG1L-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNDIG1L→partner) and Y-score (partner→SYNDIG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of autophagosome assembly →	+0.054	+0.246	.001	.002	3	6
BLOOD_Lymphoma	Regulation of macroautophagy →	+0.038	+0.027	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Positive regulation of autophagy →	+0.042	+0.195	<.001	.001	3	5
BLOOD_Lymphoma	Positive regulation of macroautophagy →	+0.035	+0.021	<.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of autophagosome assembly →	+0.059	+0.054	.007	.005	2	6
LUNG_NSCLC_LUAD	Response to starvation →	+0.034	+0.104	<.001	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 680 associations by consensus.

Regulation of autophagosome assembly by SYNDIG1L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →