SVIL2P

Across TCGA patient cohorts, SVIL2P mutation is significantly associated with the RNA expression of many other genes, with 1,090 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SVIL2P-associated genes across cancer lineages are MYCLP2, RNA5SP423, and MIR4477A. Each is linked with SVIL2P in more than 2 cancer types. Because this analysis shows association rather than direction, both SVIL2P-to-partner and partner-to-SVIL2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYCLP2 grouped by SVIL2P-low versus SVIL2P-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SVIL2P→partner) and Y-score (partner→SVIL2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MYCLP2 →	+0.040	+3.989	.001	.002	3	3
LUSC	RNA5SP423 →	+0.378	+4.412	.002	.006	3	3
SKCM	MIR4477A →	+0.559	+2.926	<.001	<.001	3	2
LUSC	SLC25A15P1 →	+0.247	+3.517	<.001	.006	3	2
BLCA	RNU6-1207P →	+0.193	+4.444	<.001	.006	3	2
SKCM	NHLRC4 →	-0.643	-3.296	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,090 associations by consensus.

MYCLP2 by SVIL2P expression — LUSC

Explore this box plot interactively →