SVIL2P

Across TCGA pan-cancer cohorts, SVIL2P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SVIL2P data layer compared with 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SVIL2P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SVIL2P expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, HNSC, and SKCM are the cancer types where SVIL2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.865	0.739	<.001	76	view →
HNSC	DFS	Tertile	All	0.790	0.606	<.001	74	view →
SKCM	OS	Median	All	0.394	0.278	<.001	61	view →
MESO	OS	Median	All	0.290	0.479	.004	33	view →
LGG	DFS	Tertile	All	0.664	0.811	.001	29	view →
KIRC	OS	Tertile	All	0.706	0.538	.003	21	view →
COAD	OS	Quartile	II,III,IV	0.387	0.696	.007	21	view →
UCS	OS	Tertile	III,IV	0.594	0.266	.010	20	view →
BLCA	OS	Quartile	All	0.499	0.702	.006	19	view →
THYM	OS	Median	All	1.000	0.628	<.001	18	view →
LUSC	DFS	Median	III,IV	0.417	0.996	.001	18	view →
ESCA	OS	Quartile	II,III,IV	0.878	0.598	.004	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SVIL2P–LUAD (DFS)

Open the LUAD breakdown →